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Kytogenics Pharmaceuticals, Inc.

Kytogenics_Scientific Advisors

Timothy D. G. Lee, Ph.D. has been a consultant for Kytogenics for the past 15 years.  Dr. Lee has spent his entire career in academia in teaching, administration and above all in research and development. From 1987 until 1991, Dr. Lee was Assistant Professor in the Department of Microbiology and Infectious Diseases on the Faculty of Medicine at the University of Calgary. From 1991 until the present, he was first Associate Professor in the Department of Microbiology and Immunology of Dalhousie, and second, a research professor in the same and lastly from 1992 the Director of Research at that institution. His teaching career has included courses in molecular immunology and the principles of transplantation and supervisory teaching of a plethora of graduate students, and current and post honors students. At the University, Dr. Lee is the Director of Research, Transplantation and Immunology Research Laboratory, Member of the Research Committee, Member of the Immunology Program Committee, Chairman of COPS Immunology Curricular Committee and Chairman of the Senate Subcommittee on on-line learning.

With all of this, Dr. Lee's major efforts are dedicated to research in the fields of Microbiology and Immunology for surgical applications. Dr. Lee conducts this research on behalf of the University and under grants from foundations and corporations such as Kytogenics.

Dr. Lee received a Bachelor of Science Degree with Honors in Microbiology from the University of Toronto 1975, a Masters Degree in Microbiology also from the University of Toronto 1977 and a Ph.D. in Immunology from the University of Glasgow, Glasgow, Scotland 1982. Dr. Lee is also the author of more than 75 articles and papers related to these studies in the fields of Microbiology and Immunology.

Maya Thanou, Ph.D.  is a lecturer at the Genetic Therapies Centre, Department of Chemistry, Imperial College in London.  Previously she was a lecturer with the Center for Polymer Therapeutics, at Cardiff University in Wales.  She was also a Member of the Drug Delivery Group at Cardiff University.  Her research interests are threefold including 1) design and development of biocompatible polymers for the oral delivery and absorption enhancement of macromolecular drugs (peptides, heparins, oligonucleotides);  2) development of gene delivery systems using novel modifications of cationic polymers of natural origin; and 3) development of polymeric drug carriers covalently linked to ligands for targeting the urokinase type Plasminogen Activator Receptor.  Dr.  Thanou has published numerous papers and abstracts. She has a Ph.D. in Pharmaceutical Technology/Drug Delivery from Leiden University in the Netherlands and a M.Sc. in Pharmacy from Aristotle University in Thessaloniki, Greece.

Michael P. Diamond, MD is considered by many in the medical profession to be among the leading practitioners and researchers in the field of surgical bio-materials, specializing in surgical solvents and adhesions. Dr. Diamond is currently the Kamran S. Moghissi Professor of Obstetrics and Gynecology, Associate Chairman and the Vice Chairman for Research for the Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Wayne State University/Detroit Medical Center in Detroit MI. From 1985 until 1992, he was the Assistant Professor and then Associate Professor in the Division of Reproductive Endocrinology and Infertility for the Department of Obstetrics and Gynecology at the Yale University School of Medicine affiliated with the Yale-New Haven Hospital. From 1992 until 1994, Dr. Diamond was the Associate Professor of the Department of Molecular Physiology an Biophysics, the Department of Surgery and the Department of Obstetrics and Gynecology as well as the Director of Research at the Vanderbilt University Medical Center in Nashville, TN. In 1994, he commenced his appointments at the Wayne State University School of Medicine. He has published over 90 Manuscripts, 100 Chapters, 300 Abstracts and has edited over 15 books. He has served on several editorial boards as a reviewer for numerous journals and has been Chairperson of numerous National and International Symposiums. Dr. Diamond also served as a member of the Obstetrics and Gynecology Device Panel of the Medical Device Advisory Committee of the FDA from 1995-1999 and continues to serve as a consultant. Dr. Diamond received a B.A. Degree in Biochemistry from Vassar College, Poughkeepsie NY 1977 and a MD from Vanderbilt University Medical School 1981. He received post-graduate training as an intern and resident in the Department of Obstetrics and Gynecology at Vanderbilt University 1981-1985 and as a Fellow, Reproductive Endocrinology and Infertility at the Department of Obstetrics and Gynecology at Yale University School of Medicine 1985-1987.

Clive M. Elson, Ph.D. has spent his entire career as a Professor of Analytical Chemistry and as an executive officer involved in scientific and technical matters mainly for Nova Chem and Kytogenics. In 1993, he began extensive research work on the application of Chitin relating to adhesions. Dr. Elson was an Associate Professor (1978-86) and Professor (1986-present) at Saint Mary's University in Halifax, Nova Scotia; a 10,000 student mainly undergraduate institution. From 1993-2002 Dr. Elson was the Senior Vice President, Chief Scientific Officer and a Director of Kytogenics. Dr. Elson has published several patents and patent applications including others with Drs. Lee and Kydonieus. Dr. Elson received a BS Degree in Chemistry with Honors from the University of Toronto 1968 and a Ph.D. in Chemistry from Queens University 1971. He received a post-doctoral Fellow at the University of Sussex (UK) 1971. He was formerly a member of the Board of Directors of the Canadian Agricultural New Uses Council 1995-98 and is a member of the Biotech Working Groups of Nova Scotia (1994-present).

Peter V. Hauschka, Ph.D. has been the Chairman of Kytogenics' Scientific Advisory Board since 1993. Dr. Hauschka currently holds appointments as Associate Professor of Oral Biology and Pathophysiology on the faculty of Medicine at Harvard University, an Associate Professor of Oral Biology and Pathophysiology at the Harvard School of Dental Medicine, Boston, and as a Senior Research Associate in Orthopedic Surgery at the Children's Hospital in Boston. He has been associated with the Harvard Medical School and the Children's Hospital for his entire career. He has published with others 69 journal articles, 23 reviews/chapters/proceedings, 1 patent and 40 additional abstracts and other listed items. In addition, he has been a principal investigator on 24 grant awards and has generated over $14 million in total grant awards. Dr. Hauschka received a B.A. Degree in Biophysics from Amherst College 1964 and a Ph.D. from John Hopkins University in Biochemistry Cum Laude 1969.

George Zazanis, MD is a neurosurgeon and Professor of Neurosurgery at the Robert Wood Johnson Medical Centre in New Brunswick, New Jersey and is a Professor of Clinical Surgery at the University of Medicine and Dentistry at the Robert Wood Johnson Medical School. Dr. Zazanis is the husband of Marina Zazanis.